I don't remember it ever getting annoying when we died and you respawn with only the equipment and ammo that you had when you died, so it is not a good idea to die over and over again. I'd recommend only two players at a time but you may find it plays well enough with more people.When you die in multiplayer you return to the last healing chamber thingy that you reached which works quite well because there is usually always one close by. I think with more than two you will find yourself running out of ammo a lot but the game would probably be easier since the number of enemies does not increase. We played over a LAN rather than over the net because as an RPG it was a lot easier to communicate in person regarding equipment and story elements rather than through text or voice chat.I'm not sure how it would work for four people but with two the difficulty was just fine. We played for about 8-10 hours at a time and it tooks us a couple of weekends to finish. I played the entire System Shock 2 game with a friend of mine and it was one of the greatest gaming experiences ever.

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